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Patatin-Like Phospholipase Domain-Containing Protein 6 (PNPLA6) Antibody
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Catalogue No: abx028705
Price:
US$326.25
(Size: 80 µl)
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PNPLA6 is a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Research Articles on Patatin-Like Phospholipase Domain-Containing Protein 6 (PNPLA6)
| Target | Patatin-Like Phospholipase Domain-Containing Protein 6 (PNPLA6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1000-1029 amino acids from the C-terminal region of human PNPLA6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8IY17 (UniProt, ExPASy) |
| UniProt Entry Name | PLPL6_HUMAN |
| Gene Symbol | PNPLA6 |
| GeneID | 10908 |
| OMIM | 215470 |
| HGNC | 16268 |
| KEGG | hsa:10908 |
| String | 9606.ENSP00000407509 |
| Molecular Weight | Calculated MW: 151 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse PNPLA6. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |