DNA Polymerase Delta 3, Accessory Subunit (POLD3) Antibody

POLD3 Antibody is a Rabbit Polyclonal antibody against POLD3. This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.

Target	DNA Polymerase Delta 3, Accessory Subunit (POLD3)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/100 - 1/500, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 197-466 of human POLD3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15054 (UniProt, ExPASy)
UniProt Secondary AC	B7ZAI6, Q32MZ9, Q32N00
UniProt Entry Name	DPOD3_HUMAN
Gene Symbol	POLD3
GeneID	10714
NCBI Accession	NP_006582.1
KEGG	hsa:10714
String	9606.ENSP00000263681
Molecular Weight	Calculated MW: 51 kDa Observed MW: 51 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DNA Polymerase Delta 3, Accessory Subunit (POLD3)

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