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DNA Polymerase Kappa (POLK) Antibody
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Catalogue No: abx004686
Price:
US$348.00
(Size: 60 µl)
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POLK Antibody is a Rabbit Polyclonal antibody against POLK. External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007.
Research Articles on DNA Polymerase Kappa (POLK)
| Target | DNA Polymerase Kappa (POLK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human POLK |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UBT6 (UniProt, ExPASy) |
| UniProt Entry Name | POLK_HUMAN |
| Gene Symbol | POLK |
| GeneID | 51426 |
| NCBI Accession | NP_057302.1 |
| String | 9606.ENSP00000241436 |
| Molecular Weight | Calculated MW: 42 kDa/52 kDa/54 kDa/55 kDa/76 kDa/88 kDa/98 kDa Observed MW: 80 kDa/110 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
