DNA-Directed RNA Polymerase II Subunit RPB2 (POLR2B) Antibody

DNA-Directed RNA Polymerase II Subunit RPB2 (POLR2B) Antibody is a rabbit polyclonal antibody against DNA-Directed RNA Polymerase II Subunit RPB2 (POLR2B). This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].

Target	DNA-Directed RNA Polymerase II Subunit RPB2 (POLR2B)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 797-826 amino acids from the Central region of human POLR2B.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30876 (UniProt, ExPASy)
UniProt Secondary AC	A8K1A8, Q8IZ61
UniProt Entry Name	RPB2_HUMAN
Gene Symbol	POLR2B
GeneID	5431
OMIM	180661
HGNC	9188
KEGG	hsa:5431
Ensembl	ENSG00000047315
String	9606.ENSP00000370625
Molecular Weight	Calculated MW: 134 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse POLR2B.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DNA-Directed RNA Polymerase II Subunit RPB2 (POLR2B)

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