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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody
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Catalogue No: abx028042
Price:
US$326.25
(Size: 80 µl)
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This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.
Research Articles on DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E)
| Target | DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human POLR2E. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19388 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6L4, D6W5Y1, O43380, Q6PIH5, Q9BT06 |
| UniProt Entry Name | RPAB1_HUMAN |
| Gene Symbol | POLR2E |
| KEGG | hsa:5434 |
| String | 9606.ENSP00000478303 |
| Molecular Weight | Calculated MW: 24.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat POLR2E. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |