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DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody
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Catalogue No: abx001458
Price:
US$203.00
(Size: 20 µl)
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POLR2E Antibody is a Rabbit Polyclonal antibody against POLR2E. This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.
Research Articles on DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E)
| Target | DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/100 - 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POLR2E. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19388 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6L4, D6W5Y1, O43380, Q6PIH5, Q9BT06 |
| UniProt Entry Name | RPAB1_HUMAN |
| Gene Symbol | POLR2E |
| GeneID | 5434 |
| NCBI Accession | NP_002686.2 |
| KEGG | hsa:5434 |
| String | 9606.ENSP00000478303 |
| Molecular Weight | Calculated MW: 25 kDa Observed MW: 26 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |