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Serum Paraoxonase / Arylesterase 1 (PON1) Antibody
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Catalogue No: abx025847
Price:
US$326.25
(Size: 80 µl)
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The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
Research Articles on Serum Paraoxonase / Arylesterase 1 (PON1)
| Target | Serum Paraoxonase / Arylesterase 1 (PON1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 118-145 amino acids from the Central region of human PON1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P27169 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RA40, Q16052, Q6B0J6, Q9UCB1 |
| UniProt Entry Name | PON1_HUMAN |
| Gene Symbol | PON1 |
| KEGG | hsa:5444 |
| String | 9606.ENSP00000222381 |
| Molecular Weight | Calculated MW: 39.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |