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Protection of Telomeres Protein 1 (POT1) Antibody
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Catalogue No: abx001265
Price:
US$217.50
(Size: 20 µl)
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POT1 Antibody is a Rabbit Polyclonal antibody against POT1. Protection of telomeres 1(POT1)is a conserved protein that binds the G-rich stand of its own telomeric repeat sequence, with a role in protecting chromosome ends. It's housekeeping gene that is required to ensure the integrity of chromosome ends in all cells. It's a component of the telomerase ribonucleoprotein(RNP) complex that is esential for the replication of chromosome termini. It consists the TRF1 compex that is involved in the regulation of telomere length by cis-inhibition of telomerase.
Research Articles on Protection of Telomeres Protein 1 (POT1)
| Target | Protection of Telomeres Protein 1 (POT1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NUX5 (UniProt, ExPASy) |
| UniProt Secondary AC | O95018, Q5MJ36, Q9H662, Q9NW19, Q9UG95 |
| UniProt Entry Name | POTE1_HUMAN |
| Gene Symbol | POT1 |
| GeneID | 25913 |
| NCBI Accession | NP_056265.2 |
| String | 9606.ENSP00000350249 |
| Molecular Weight | Calculated MW: 71 kDa Observed MW: 75 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 3.95 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |