POU Class 6 Homeobox 2 (POU6F2) Antibody

This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target	POU Class 6 Homeobox 2 (POU6F2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P78424 (UniProt, ExPASy)
UniProt Secondary AC	A4D1W2, C4AMB9, P78425, Q75ME8, Q86UM6, Q9UDS7
UniProt Entry Name	PO6F2_HUMAN
NCBI Accession	NP_001159490.1 NP_009183.3
KEGG	hsa:11281
String	9606.ENSP00000384004
Molecular Weight	Calculated MW: 73.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on POU Class 6 Homeobox 2 (POU6F2)

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