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Peroxisome Proliferator Activated Receptor Alpha (PPARA) Antibody
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Catalogue No: abx002244
Price:
US$203.00
(Size: 20 µl)
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PPARA Antibody is a Rabbit Polyclonal antibody against Peroxisome Proliferator Activated Receptor Alpha (PPARA). Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
Research Articles on Peroxisome Proliferator Activated Receptor Alpha (PPARA)
| Target | Peroxisome Proliferator Activated Receptor Alpha (PPARA) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human PPARα. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q07869 (UniProt, ExPASy) |
| UniProt Secondary AC | B0G0X3, Q16241, Q6I9S0, Q92486, Q92689, Q9Y3N1 |
| UniProt Entry Name | PPARA_HUMAN |
| Gene Symbol | PPARA |
| GeneID | 5465 |
| NCBI Accession | NP_001001928.1 |
| KEGG | hsa:5465 |
| String | 9606.ENSP00000385523 |
| Molecular Weight | Calculated MW: 52 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |