Amidophosphoribosyltransferase (PPAT) Antibody

PPAT Antibody is a Rabbit Polyclonal antibody against PPAT. The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region.

Target	Amidophosphoribosyltransferase (PPAT)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPAT.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q06203 (UniProt, ExPASy)
UniProt Entry Name	PUR1_HUMAN
Gene Symbol	PPAT
GeneID	5471
NCBI Accession	NP_002694.3
KEGG	hsa:5471
String	9606.ENSP00000264220
Molecular Weight	Calculated MW: 57 kDa Observed MW: 57 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Amidophosphoribosyltransferase (PPAT)

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