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PPFIA Binding Protein 1 (PPFIBP1) Antibody
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Catalogue No: abx029540
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Research Articles on PPFIA Binding Protein 1 (PPFIBP1)
| Target | PPFIA Binding Protein 1 (PPFIBP1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 588-617 amino acids from the Central region of human PPFIBP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q86W92 (UniProt, ExPASy) |
| UniProt Secondary AC | O75336, Q86X70, Q9NY03, Q9ULJ0 |
| UniProt Entry Name | LIPB1_HUMAN |
| Gene Symbol | PPFIBP1 |
| KEGG | hsa:8496 |
| String | 9606.ENSP00000314724 |
| Molecular Weight | Calculated MW: 114 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse PPFIBP1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |