Periplakin (PPL) Antibody

PPL Antibody is a Rabbit Polyclonal antibody against PPL. The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

Target	Periplakin (PPL)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PPL.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O60437 (UniProt, ExPASy)
UniProt Secondary AC	O60314, O60454, Q14C98
UniProt Entry Name	PEPL_HUMAN
Gene Symbol	PPL
GeneID	5493
NCBI Accession	NP_002696.3
KEGG	hsa:5493
String	9606.ENSP00000340510
Molecular Weight	Calculated MW: 205 kDa Observed MW: 205 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Periplakin (PPL)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue