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Protoporphyrinogen Oxidase (PPOX) Antibody
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Catalogue No: abx004892
Price:
US$217.50
(Size: 20 µl)
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PPOX Antibody is a Rabbit Polyclonal antibody against PPOX. This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Research Articles on Protoporphyrinogen Oxidase (PPOX)
| Target | Protoporphyrinogen Oxidase (PPOX) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PPOX. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P50336 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DVG0, Q5VTW8 |
| UniProt Entry Name | PPOX_HUMAN |
| Gene Symbol | PPOX |
| GeneID | 5498 |
| NCBI Accession | NP_001116236.1 |
| KEGG | hsa:5498 |
| String | 9606.ENSP00000356978 |
| Molecular Weight | Calculated MW: 51 kDa Observed MW: 51 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |