Protein Phosphatase 1 Regulatory Subunit 8 (PPP1R8) Antibody

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Catalogue No: abx005140
Price: US$435.00
(Size: 100 µl)

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Datasheet SDS
PPP1R8 Antibody is a Rabbit Polyclonal antibody against PPP1R8. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Target Protein Phosphatase 1 Regulatory Subunit 8 (PPP1R8)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-209 of human PPP1R8.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q12972 (UniProt, ExPASy)
UniProt Secondary AC Q5TEJ2, Q5TEJ4, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0
UniProt Entry Name PP1R8_HUMAN
Gene Symbol PPP1R8
GeneID 5511
NCBI Accession NP_612568.1
KEGG hsa:5511
String 9606.ENSP00000311677
Molecular Weight Calculated MW: 38 kDa
Observed MW: 40 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Protein Phosphatase 1 Regulatory Subunit 8 (PPP1R8)
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