Serine/Threonine-Protein Phosphatase 2A 56 kDa Regulatory Subunit Alpha Isoform (PPP2R1A) Antibody

PPP2R1A Antibody is a Rabbit Polyclonal antibody against PPP2R1A. This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Target	Serine/Threonine-Protein Phosphatase 2A 56 kDa Regulatory Subunit Alpha Isoform (PPP2R1A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PP2A-Aalpha/PR65α/PP2A-Aα/PR65α/PPP2R1A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30153 (UniProt, ExPASy)
UniProt Secondary AC	Q13773, Q6ICQ3, Q96DH3
UniProt Entry Name	2AAA_HUMAN
Gene Symbol	PPP2R1A
GeneID	5518
NCBI Accession	NP_055040.2
KEGG	hsa:5518
String	9606.ENSP00000324804
Molecular Weight	Calculated MW: 65 kDa Observed MW: 65 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine/Threonine-Protein Phosphatase 2A 56 kDa Regulatory Subunit Alpha Isoform (PPP2R1A)

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