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Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Antibody
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Catalogue No: abx011399
Price:
US$420.50
(Size: 100 µl)
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Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4)
| Target | Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PPP2R4 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15257 (UniProt, ExPASy) |
| UniProt Entry Name | PTPA_HUMAN |
| Gene Symbol | PTPA |
| GeneID | 5524 |
| OMIM | 600756 |
| HGNC | 9308 |
| KEGG | hsa:5524 |
| Ensembl | ENSG00000119383 |
| String | 9606.ENSP00000377036 |
| Molecular Weight | 41 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |