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Protein Phosphatase 4 Regulatory Subunit 2 (PPP4R2) Antibody
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Catalogue No: abx030332
Price:
US$290.00
(Size: 80 µl)
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Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Research Articles on Protein Phosphatase 4 Regulatory Subunit 2 (PPP4R2)
| Target | Protein Phosphatase 4 Regulatory Subunit 2 (PPP4R2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NY27 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K1I6, Q2TAJ9, Q498B8, Q8WXX6 |
| UniProt Entry Name | PP4R2_HUMAN |
| Gene Symbol | PPP4R2 |
| String | 9606.ENSP00000349124 |
| Molecular Weight | Calculated MW: 46.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |