Protein Phosphatase 4 Regulatory Subunit 2 (PPP4R2) Antibody

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Target	Protein Phosphatase 4 Regulatory Subunit 2 (PPP4R2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NY27 (UniProt, ExPASy)
UniProt Secondary AC	A8K1I6, Q2TAJ9, Q498B8, Q8WXX6
UniProt Entry Name	PP4R2_HUMAN
Gene Symbol	PPP4R2
String	9606.ENSP00000349124
Molecular Weight	Calculated MW: 46.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Phosphatase 4 Regulatory Subunit 2 (PPP4R2)

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