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Progesterone Receptor (PR) Antibody
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Catalogue No: abx011372
Price:
US$427.75
(Size: 100 µl)
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PR (progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Research Articles on Progesterone Receptor (PR)
| Target | Progesterone Receptor (PR) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of PR expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06401 (UniProt, ExPASy) |
| UniProt Secondary AC | A7LQ08, A7X8B0, B4E3T0, Q8TDS3, Q9UPF7 |
| UniProt Entry Name | PRGR_HUMAN |
| Gene Symbol | PGR |
| GeneID | 5241 |
| OMIM | 607311 |
| HGNC | 8910 |
| KEGG | hsa:5241 |
| Ensembl | ENSG00000082175 |
| String | 9606.ENSP00000325120 |
| Molecular Weight | 99 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |