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PR Domain Zinc Finger Protein 2 (PRDM2) Antibody
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Catalogue No: abx025172
Price:
US$290.00
(Size: 80 µl)
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This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on PR Domain Zinc Finger Protein 2 (PRDM2)
| Target | PR Domain Zinc Finger Protein 2 (PRDM2) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, ChIP |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000, ChIP: 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant GST fusion protein encoding 1-347 AA of human PRDM2 (RIZ1). |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13029 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AJZ4, B5MC68, Q13149, Q14550, Q5THJ1, Q5VUL9 |
| UniProt Entry Name | PRDM2_HUMAN |
| NCBI Accession | NP_001007258.1 NP_001129082.1 NP_036363.2 NP_056950.2 |
| KEGG | hsa:7799 |
| String | 9606.ENSP00000235372 |
| Molecular Weight | Calculated MW: 189 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | This antibody is specific for RIZ1, it does not recognise the isoform beta (RIZ2). |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |