PR Domain Zinc Finger Protein 2 (PRDM2) Antibody

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Catalogue No: abx026566
Price: US$326.25
(Size: 80 µl)

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PR Domain Zinc Finger Protein 2 (PRDM2) Antibody
PR Domain Zinc Finger Protein 2 (PRDM2) Antibody

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Datasheet SDS
PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein; RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.

Target PR Domain Zinc Finger Protein 2 (PRDM2)
Clonality Polyclonal
Reactivity Rat
Tested Applications ELISA, IHC
Host Rabbit
Recommended dilutions IHC-P: 1/100 - 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant GST fusion protein encoding 245-573 AA of rat Riz1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13029 (UniProt, ExPASy)
UniProt Secondary AC B1AJZ4, B5MC68, Q13149, Q14550, Q5THJ1, Q5VUL9
UniProt Entry Name PRDM2_HUMAN
NCBI Accession NP_001007258.1 NP_001129082.1 NP_036363.2 NP_056950.2
KEGG hsa:7799
String 9606.ENSP00000235372
Molecular Weight Calculated MW: 188 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity This antibody also recognises the isoform beta (Riz2) of PRDM2 (185 kDa).
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on PR Domain Zinc Finger Protein 2 (PRDM2)
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