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Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) Antibody
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Catalogue No: abx032926
Price:
US$326.25
(Size: 80 µl)
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PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
Research Articles on Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP)
| Target | Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 119-148 amino acids from the Central region of human PRELP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P51888 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6FG38 |
| UniProt Entry Name | PRELP_HUMAN |
| NCBI Accession | NP_002716.1 NP_958505.1 |
| KEGG | hsa:5549 |
| String | 9606.ENSP00000343924 |
| Molecular Weight | Calculated MW: 43.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |