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5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2) Antibody
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Catalogue No: abx025250
Price:
US$623.50
(Size: 100 µl)
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This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. This antibody is supplied as crude ascites.
Research Articles on 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2)
| Target | 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human PRKAA2 recombinant protein. |
| Isotype | IgG2a Kappa |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54646 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9H1E8, Q9UD43 |
| UniProt Entry Name | AAPK2_HUMAN |
| KEGG | hsa:5563 |
| String | 9606.ENSP00000360290 |
| Molecular Weight | Calculated MW: 62.3 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Please enquire. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |