5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2) Antibody

REQUEST MORE INFO
Catalogue No: abx025944
Price: US$290.00
(Size: 80 µl)

Click on the image to see the image legend

Available Options

* Size:


Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Target 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 145-173 amino acids from the Central region of human PRKAA2 (Thr172).
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P54646 (UniProt, ExPASy)
UniProt Secondary AC Q9H1E8, Q9UD43
UniProt Entry Name AAPK2_HUMAN
KEGG hsa:5563
String 9606.ENSP00000360290
Molecular Weight Calculated MW: 62.3 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat and Pig PRKAA2.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 (PRKAA2)


Write a review

Tags:
(Click to show)