Protein Kinase, AMP Activated Beta 2 (PRKAB2) Antibody

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Catalogue No: abx005275
Price: US$710.50
(Size: 100 µl)
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Western blot analysis of various lysates using PRKAB2 Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 10s.
Protein Kinase, AMP Activated Beta 2 (PRKAB2) Antibody Protein Kinase, AMP Activated Beta 2 (PRKAB2) Antibody Protein Kinase, AMP Activated Beta 2 (PRKAB2) Antibody

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Datasheet SDS
PRKAB2 Antibody is a Rabbit Polyclonal antibody against PRKAB2. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.

Target Protein Kinase, AMP Activated Beta 2 (PRKAB2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IF/ICC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human PRKAB2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O43741 (UniProt, ExPASy)
UniProt Secondary AC A8K9V5, B4DH06, Q5VXY0
UniProt Entry Name AAKB2_HUMAN
Gene Symbol PRKAB2
GeneID 5565
NCBI Accession NP_005390.1
KEGG hsa:5565
String 9606.ENSP00000254101
Molecular Weight Calculated MW: 30 kDa
Observed MW: 33 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Protein Kinase, AMP Activated Beta 2 (PRKAB2)
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