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5'-AMP-Activated Protein Kinase Subunit Gamma-1 (PRKAG1) Antibody
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Catalogue No: abx005507
Price:
US$348.00
(Size: 60 µl)
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PRKAG1 Antibody is a Rabbit Polyclonal antibody against PRKAG1. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Research Articles on 5'-AMP-Activated Protein Kinase Subunit Gamma-1 (PRKAG1)
| Target | 5'-AMP-Activated Protein Kinase Subunit Gamma-1 (PRKAG1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PRKAG1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54619 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DDT7, Q8N7V9 |
| UniProt Entry Name | AAKG1_HUMAN |
| Gene Symbol | PRKAG1 |
| GeneID | 5571 |
| NCBI Accession | NP_002724.1 |
| KEGG | hsa:5571 |
| String | 9606.ENSP00000323867 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
