+44 (0) 1223 755950
+1 832 327 7413
Protein Arginine N-Methyltransferase 1 (PRMT1) Antibody
REQUEST MORE INFO
Catalogue No: abx000978
Price:
US$203.00
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
PRMT1 Antibody is a Rabbit Polyclonal antibody against PRMT1. This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
Research Articles on Protein Arginine N-Methyltransferase 1 (PRMT1)
| Target | Protein Arginine N-Methyltransferase 1 (PRMT1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 270-371 of human PRMT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99873 (UniProt, ExPASy) |
| UniProt Entry Name | ANM1_HUMAN |
| Gene Symbol | PRMT1 |
| GeneID | 3276 |
| OMIM | 602950 |
| NCBI Accession | NP_001527.3 |
| HGNC | 5187 |
| KEGG | hsa:3276 |
| Ensembl | ENSG00000126457 |
| String | 9606.ENSP00000406162 |
| Molecular Weight | Calculated MW: 42 kDa Observed MW: 42 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |