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Vitamin K-Dependent Protein C (PROC) Antibody
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Catalogue No: abx027455
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
Research Articles on Vitamin K-Dependent Protein C (PROC)
| Target | Vitamin K-Dependent Protein C (PROC) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 177-206 amino acids from the Central region of human PROC. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04070 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DPQ7, Q15189, Q15190, Q16001, Q53S74, Q9UC55 |
| UniProt Entry Name | PROC_HUMAN |
| KEGG | hsa:5624 |
| String | 9606.ENSP00000234071 |
| Molecular Weight | Calculated MW: 52.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |