Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4) Antibody

Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4) Antibody is a Rabbit Polyclonal antibody for the detection of PCSK4.

Proprotein convertase subtilysin/Kexin Type4 (PCSK4) is a protein convertase enzymes in spermatozoa acrosome membrane, it has an important role in the acrosome reaction through endoproteolytic process that converts the precursor proteins into bioactive protein as a necessary substance to penetrate on the zona pellucida (PMID: 16040806 ). The molecular mass of pro-PCSK4 is 72kDa, and mature PCSK4 is 54 kDa (PMID: 16040806, 19109312).

Target	Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	proprotein convertase subtilisin/kexin type 4
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q6UW60 (UniProt, ExPASy)
UniProt Secondary AC	Q8IY88, Q9UF79
UniProt Entry Name	PCSK4_HUMAN
GeneID	54760
KEGG	hsa:54760
String	9606.ENSP00000300954
Molecular Weight	Observed MW: 26 kDa, 72 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4)

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