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Prostaglandin E2 Receptor EP3 Subtype (PE2R3) Antibody
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Catalogue No: abx215171
Price:
US$406.00
(Size: 100 µg)
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Prostaglandin E2 Receptor EP3 Subtype (PE2R3) Antibody is a Rabbit Polyclonal antibody for the detection of PTGER3. Receptor for prostaglandin E2 (PGE2) ; the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
Research Articles on Prostaglandin E2 Receptor EP3 Subtype (PE2R3)
| Target | Prostaglandin E2 Receptor EP3 Subtype (PE2R3) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | prostaglandin E receptor 3(subtype EP3) |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P43115 (UniProt, ExPASy) |
| UniProt Entry Name | PE2R3_HUMAN |
| Gene Symbol | PTGER3 |
| GeneID | 5733 |
| OMIM | 176806 |
| HGNC | 9595 |
| KEGG | hsa:5733 |
| Ensembl | ENSG00000050628 |
| String | 9606.ENSP00000349003 |
| Molecular Weight | Observed MW: 55 kDa, 70 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |