Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody

Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody is a Mouse Monoclonal antibody for the detection of COX2.

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Target	Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/100 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	prostaglandin-endoperoxide synthase 2
Isotype	IgG2a
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P35354 (UniProt, ExPASy)
UniProt Secondary AC	A8K802, Q16876
UniProt Entry Name	PGH2_HUMAN
Gene Symbol	PTGS2
GeneID	5743
OMIM	600262
HGNC	9605
KEGG	hsa:5743
Ensembl	ENSG00000073756
String	9606.ENSP00000356438
Molecular Weight	Observed MW: 68 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)

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