Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody

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Catalogue No: abx010596
Price: US$406.00
(Size: 100 µg)

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WB analysis of various lysates, using PTGS2 antibody (1/600 dilution).
Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody

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Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody is a Rabbit Polyclonal antibody for the detection of COX2.

COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa (PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage (PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains (PMID:14724276 ).

Target Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen prostaglandin-endoperoxide synthase 2(prostaglandin G/H synthase and cyclooxygenase)
Isotype IgG
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC P35354 (UniProt, ExPASy)
UniProt Secondary AC A8K802, Q16876
UniProt Entry Name PGH2_HUMAN
Gene Symbol PTGS2
GeneID 5743
OMIM 600262
HGNC 9605
KEGG hsa:5743
Ensembl ENSG00000073756
String 9606.ENSP00000356438
Molecular Weight Observed MW: 50 kDa, 80 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)
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