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Human 26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13) Protein
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Catalogue No: abx073444
Price:
US$261.00
(Size: 5 µg)
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26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13) is a recombinant enzyme. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13)
| Target | 26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13) |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | E. coli |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
| Purity | > 90% (SDS-PAGE) |
| Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UNM6 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KT15, O75831, Q53XU2, Q9UNV3 |
| UniProt Entry Name | PSD13_HUMAN |
| Gene Symbol | PSMD13 |
| GeneID | 5719 |
| OMIM | 603481 |
| NCBI Accession | NP_002808.3 NM_002817.3 [Q9UNM6-1] NP_787128.2 NM_175932.2 [Q9UNM6-2] |
| HGNC | 9558 |
| Ensembl | ENSG00000185627 |
| Sequence | MGSSHHHHHH SSGLVPRGSH MGSMKDVPGF LQQSQNSGPG QPAVWHRLEE LYTKKLWHQL TLQVLDFVQD PCFAQGDGLI KLYENFISEF EHRVNPLSLV EIILHVVRQM TDPNVALTFL EKTREKVKSS DEAVILCKTA IGALKLNIGD LQVTKETIED VEEMLNNLPG VTSVHSRFYD LSSKYYQTIG NHASYYKDAL RFLGCVDIKD LPVSEQQERA FTLGLAGLLG EGVFNFGELL MHPVLESLRN TDRQWLIDTL YAFNSGNVER FQTLKTAWGQ QPDLAANEAQ LLRKIQLLCL MEMTFTRPAN HRQLTFEEIA KSAKITVNEV ELLVMKALSV GLVKGSIDEV DKRVHMTWVQ PRVLDLQQIK GMKDRLEFWC TDVKSMEMLV EHQAHDILT. |
| Activity | Not tested |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |