26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) Antibody

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Catalogue No: abx128466
US$319.00 US$223.30
(Size: 100 µl)

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Datasheet SDS
Proteasome 26S Subunit, Non ATPase 4 Antibody is a Rabbit Polyclonal against Proteasome 26S Subunit, Non ATPase 4. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21.

Target 26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen PSMD4 (Met1-Lys377)
Form Liquid
Purification Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P55036 (UniProt, ExPASy)
UniProt Secondary AC D3DV16, Q5VWC5, Q9NS92
UniProt Entry Name PSMD4_HUMAN
Gene Symbol PSMD4
GeneID 5710
OMIM 601648
NCBI Accession NP_002801.1 NM_002810.2
HGNC 9561
KEGG hsa:5710
Ensembl ENSG00000159352
String 9606.ENSP00000357879
Buffer 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability Shipped within 5-7 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4)
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