Human 26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5) Protein

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Catalogue No: abx166684
Price: US$246.50
(Size: 10 µg)

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Datasheet SDS
Proteasome 26S Subunit, Non ATPase 5 Protein is a recombinant Human protein expressed in E. coli. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.

Target 26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5)
Origin Human
Expression Recombinant
Tested Applications WB, SDS-PAGE
Host E. coli
Conjugation Unconjugated
Form Lyophilized
Purity > 95%
Reconstitution To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Storage Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q16401 (UniProt, ExPASy)
UniProt Secondary AC B4DZM8, Q15045, Q4VXG8
UniProt Entry Name PSMD5_HUMAN
Gene Symbol PSMD5
GeneID 5711
OMIM 604452
NCBI Accession NP_001257356.1 NM_001270427.1 NP_005038.1 NM_005047.3
HGNC 9563
KEGG hsa:5711
Ensembl ENSG00000095261
String 9606.ENSP00000210313
Molecular Weight Calculated MW: 25.9 kDa
Sequence Fragment Lys143-Arg341
Tag N-terminal His tag
Buffer Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Activity Not tested
Concentration Prior to lyophilization: 200 µg/ml
Availability Shipped within 5-7 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 5 (PSMD5)
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