26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) Antibody

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Catalogue No: abx179112
US$391.50 US$274.05
(Size: 100 µl)

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26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) Antibody

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Datasheet SDS
Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Antibody is a Rabbit polyclonal antibody against Human Proteasome 26S Subunit, Non ATPase 8 (PSMD8). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

Target 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Form Liquid
Purification Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P48556 (UniProt, ExPASy)
UniProt Secondary AC B4DX18, Q6P1L7
UniProt Entry Name PSMD8_HUMAN
Gene Symbol PSMD8
GeneID 5714
KEGG hsa:5714
String 9606.ENSP00000215071
Buffer 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability Shipped within 5-7 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)
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