+44 (0) 1223 755950
+1 832 327 7413
26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) Antibody
REQUEST MORE INFO
Catalogue No: abx179112
Price:
US$391.50
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Antibody is a Rabbit polyclonal antibody against Human Proteasome 26S Subunit, Non ATPase 8 (PSMD8). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)
| Target | 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Liquid |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48556 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DX18, Q6P1L7 |
| UniProt Entry Name | PSMD8_HUMAN |
| Gene Symbol | PSMD8 |
| GeneID | 5714 |
| KEGG | hsa:5714 |
| String | 9606.ENSP00000215071 |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Note | This product is for research use only. |