Human Proteasome Subunit Alpha Type 1 (PSMA1) Protein

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Catalogue No: abx073245
Price: US$261.00
(Size: 5 µg)

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Datasheet SDS
Proteasome Subunit Alpha Type 1 (PSMA1) is a recombinant enzyme. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Target Proteasome Subunit Alpha Type 1 (PSMA1)
Origin Human
Expression Recombinant
Tested Applications SDS-PAGE
Host E. coli
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Form Liquid
Purity > 95% (SDS-PAGE)
Storage Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
UniProt Primary AC P25786 (UniProt, ExPASy)
UniProt Secondary AC A8K400, Q53YE8, Q9BRV9
UniProt Entry Name PSA1_HUMAN
KEGG hsa:5682
String 9606.ENSP00000414359
Sequence MGSSHHHHHH SSGLVPRGSH MGSMFRNQYD NDVTVWSPQG RIHQIEYAME AVKQGSATVG LKSKTHAVLV ALKRAQSELA AHQKKILHVD NHIGISIAGL TADARLLCNF MRQECLDSRF VFDRPLPVSR LVSLIGSKTQ IPTQRYGRRP YGVGLLIAGY DDMGPHIFQT CPSANYFDCR AMSIGARSQS ARTYLERHMS EFMECNLNEL VKHGLRALRE TLPAEQDLTT KNVSIGIVGK DLEFTIYDDD DVSPFLEGLE ERPQRKAQPA QPADEPAEKA DEPMEH
Activity Not tested
Availability Shipped within 5-10 working days.
Note This product is for research use only.

Not for human consumption, cosmetic, therapeutic or diagnostic use.
Research Articles on Proteasome Subunit Alpha Type 1 (PSMA1)


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