Proteasome Subunit Alpha Type 7 (PSMA7) Antibody

Proteasome Subunit Alpha Type 7 (PSMA7) Antibody is a Rabbit Polyclonal antibody against Proteasome Subunit Alpha Type 7 (PSMA7). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

Target	Proteasome Subunit Alpha Type 7 (PSMA7)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant human Proteasome subunit alpha type-7 protein (5-232AA).
Isotype	IgG
Form	Liquid
Purity	> 95%
Purification	Purified by Protein G.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14818 (UniProt, ExPASy)
UniProt Secondary AC	B2R515, Q5JXJ2, Q9BR53, Q9H4K5, Q9UEU8
UniProt Entry Name	PSA7_HUMAN
Gene Symbol	PSMA7
GeneID	5688
OMIM	606607
NCBI Accession	NP_002783.1 NM_002792.3
KEGG	hsa:5688
String	9606.ENSP00000359910
Buffer	0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Proteasome Subunit Alpha Type 7 (PSMA7)

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