Human Proteasome Subunit Alpha Type 7 (PSMA7) Protein

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Catalogue No: abx073064
Price: US$261.00
(Size: 10 µg)

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Datasheet SDS
Proteasome Subunit Alpha Type 7 (PSMA7) is a recombinant enzyme. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

Target Proteasome Subunit Alpha Type 7 (PSMA7)
Origin Human
Expression Recombinant
Tested Applications SDS-PAGE
Host E. coli
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Form Liquid
Purity > 90% (SDS-PAGE)
Storage Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14818 (UniProt, ExPASy)
UniProt Secondary AC B2R515, Q5JXJ2, Q9BR53, Q9H4K5, Q9UEU8
UniProt Entry Name PSA7_HUMAN
KEGG hsa:5688
String 9606.ENSP00000359910
Sequence MGSSHHHHHH SSGLVPRGSH MSYDRAITVF SPDGHLFQVE YAQEAVKKGS TAVGVRGRDI VVLGVEKKSV AKLQDERTVR KICALDDNVC MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE FLEKNYTDEA IETDDLTIKL VIKALLEVVQ SGGKNIELAV MRRDQSLKIL NPEEIEKYVA EIEKEKEENE KKKQKKAS.
Activity Not tested
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Proteasome Subunit Alpha Type 7 (PSMA7)
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