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Human Proteasome Subunit Beta Type 4 (PSMB4) Protein
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Catalogue No: abx073730
Price:
US$261.00
(Size: 2 µg)
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Proteasome Subunit Beta Type 4 (PSMB4) is a recombinant enzyme. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
Research Articles on Proteasome Subunit Beta Type 4 (PSMB4)
| Target | Proteasome Subunit Beta Type 4 (PSMB4) |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | E. coli |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
| Purity | > 90% (SDS-PAGE) |
| Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P28070 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9L3, P31148, Q5SZS5, Q6IBI4, Q969L6 |
| UniProt Entry Name | PSB4_HUMAN |
| Gene Symbol | PSMB4 |
| GeneID | 5692 |
| OMIM | 602177 |
| HGNC | 9541 |
| KEGG | hsa:5692 |
| Ensembl | ENSG00000159377 |
| String | 9606.ENSP00000290541 |
| Sequence | MGSSHHHHHH SSGLVPRGSH MTQNPMVTGT SVLGVKFEGG VVIAADMLGS YGSLARFRNI SRIMRVNNST MLGASGDYAD FQYLKQVLGQ MVIDEELLGD GHSYSPRAIH SWLTRAMYSR RSKMNPLWNT MVIGGYADGE SFLGYVDMLG VAYEAPSLAT GYGAYLAQPL LREVLEKQPV LSQTEARDLV ERCMRVLYYR DARSYNRFQI ATVTEKGVEI EGPLSTETNW DIAHMISGFE |
| Activity | Not tested |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |