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Protein Kinase C Gamma (PRKCG) Antibody
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Catalogue No: abx239965
Price:
US$406.00
(Size: 100 µg)
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Protein Kinase C Gamma (PRKCG) Antibody is a Rabbit Polyclonal antibody for the detection of PKC gamma. Protein kinase C (PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca (2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14 (SCA14), an autosomal dominant neurodegenerative disease.
Research Articles on Protein Kinase C Gamma (PRKCG)
| Target | Protein Kinase C Gamma (PRKCG) |
| Clonality | Polyclonal |
| Reactivity | Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | protein kinase C, gamma |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P63318 (UniProt, ExPASy) |
| UniProt Secondary AC | P05697 |
| UniProt Entry Name | KPCG_MOUSE |
| Gene Symbol | PRKCG |
| KEGG | mmu:18752 |
| String | 10090.ENSMUSP00000097874 |
| Molecular Weight | Observed MW: 78 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |