Protein Kinase C Gamma (PRKCG) Antibody

Protein Kinase C Gamma (PRKCG) Antibody is a Rabbit Polyclonal antibody for the detection of PKC gamma.

Protein kinase C (PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca (2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14 (SCA14), an autosomal dominant neurodegenerative disease.

Target	Protein Kinase C Gamma (PRKCG)
Clonality	Polyclonal
Reactivity	Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	protein kinase C, gamma
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P63318 (UniProt, ExPASy)
UniProt Secondary AC	P05697
UniProt Entry Name	KPCG_MOUSE
Gene Symbol	PRKCG
KEGG	mmu:18752
String	10090.ENSMUSP00000097874
Molecular Weight	Observed MW: 78 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Protein Kinase C Gamma (PRKCG)

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