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Protein Kinase C Theta (PRKCQ) Antibody
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Catalogue No: abx239993
Price:
US$406.00
(Size: 100 µg)
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Protein Kinase C Theta (PRKCQ) Antibody is a Rabbit Polyclonal antibody for the detection of PRKCQ. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Research Articles on Protein Kinase C Theta (PRKCQ)
| Target | Protein Kinase C Theta (PRKCQ) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | PRKCQ |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q04759 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DF52, Q14DH6, Q3MJF1, Q64FY5, Q9H508, Q9H549 |
| UniProt Entry Name | KPCT_HUMAN |
| Gene Symbol | PRKCQ |
| GeneID | 5588 |
| OMIM | 600448 |
| HGNC | 9410 |
| KEGG | hsa:5588 |
| Ensembl | ENSG00000065675 |
| String | 9606.ENSP00000263125 |
| Molecular Weight | Observed MW: 85 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |