Prosaposin (PSAP) Antibody

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Catalogue No: abx011980
Price: US$427.75
(Size: 100 µl)

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Datasheet SDS
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target Prosaposin (PSAP)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/50 - 1/500, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human PSAP (AA: 325-524) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Purified from ascites by Protein G chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07602 (UniProt, ExPASy)
UniProt Secondary AC P07292, P15793, P78538, P78541, P78546, P78547, P78558, Q53Y86, Q6IBQ6, Q92739, Q92740, Q92741, Q92742
UniProt Entry Name SAP_HUMAN
Gene Symbol PSAP
GeneID 5660
OMIM 176801
HGNC 9498
KEGG hsa:5660
Ensembl ENSG00000197746
String 9606.ENSP00000378394
Molecular Weight 58.1 kDa
Buffer PBS, containing 0.05% sodium azide.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Prosaposin (PSAP)


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