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PH, SEC7 And Coiled-Coil Domain-Containing Protein 2 (PSCD2) Antibody
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Catalogue No: abx026674
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on PH, SEC7 And Coiled-Coil Domain-Containing Protein 2 (PSCD2)
| Target | PH, SEC7 And Coiled-Coil Domain-Containing Protein 2 (PSCD2) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human PSCD2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99418 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8P0, Q8IXY9, Q92958 |
| UniProt Entry Name | CYH2_HUMAN |
| Gene Symbol | CYTH2 |
| KEGG | hsa:9266 |
| String | 9606.ENSP00000408236 |
| Molecular Weight | Calculated MW: 46.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Cow CYTH2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |