+44 (0) 1223 755950
+1 832 327 7413
PC4 and SFRS1-Interacting Protein (PSIP1) Antibody
REQUEST MORE INFO
Catalogue No: abx012275
Price:
US$420.50
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.
Research Articles on PC4 and SFRS1-Interacting Protein (PSIP1)
| Target | PC4 and SFRS1-Interacting Protein (PSIP1) |
| Clonality | Monoclonal |
| Reactivity | Human, Monkey, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PSIP1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75475 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DRI9, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6 |
| UniProt Entry Name | PSIP1_HUMAN |
| GeneID | 11168 |
| KEGG | hsa:11168 |
| String | 9606.ENSP00000370109 |
| Molecular Weight | 75 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |