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Proteasome Subunit Beta Type 2 (PSMB2) Antibody
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Catalogue No: abx004200
Price:
US$348.00
(Size: 60 µl)
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PSMB2 Antibody is a Rabbit Polyclonal antibody against PSMB2. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Articles on Proteasome Subunit Beta Type 2 (PSMB2)
| Target | Proteasome Subunit Beta Type 2 (PSMB2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PSMB2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49721 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DPS0, P31145, Q9BWZ9 |
| UniProt Entry Name | PSB2_HUMAN |
| Gene Symbol | PSMB2 |
| GeneID | 5690 |
| NCBI Accession | NP_002785.1 |
| KEGG | hsa:5690 |
| String | 9606.ENSP00000362334 |
| Molecular Weight | Calculated MW: 22 kDa Observed MW: 23 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
