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Proteasome Subunit Beta Type 4 (PSMB4) Antibody
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Catalogue No: abx004358
Price:
US$217.50
(Size: 20 µl)
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PSMB4 Antibody is a Rabbit Polyclonal antibody against PSMB4. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
Research Articles on Proteasome Subunit Beta Type 4 (PSMB4)
| Target | Proteasome Subunit Beta Type 4 (PSMB4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human PSMB4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P28070 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9L3, P31148, Q5SZS5, Q6IBI4, Q969L6 |
| UniProt Entry Name | PSB4_HUMAN |
| Gene Symbol | PSMB4 |
| GeneID | 5692 |
| OMIM | 602177 |
| NCBI Accession | NP_002787.2 |
| HGNC | 9541 |
| KEGG | hsa:5692 |
| Ensembl | ENSG00000159377 |
| String | 9606.ENSP00000290541 |
| Molecular Weight | Calculated MW: 29 kDa Observed MW: 22 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |