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Proteasome Subunit Beta Type 5 (PSMB5) Antibody
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Catalogue No: abx001609
Price:
US$203.00
(Size: 20 µl)
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PSMB5 Antibody is a Rabbit Polyclonal antibody against PSMB5. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Proteasome Subunit Beta Type 5 (PSMB5)
| Target | Proteasome Subunit Beta Type 5 (PSMB5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000 - 1/7000, IHC-P: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human PSMB5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P28074 (UniProt, ExPASy) |
| UniProt Entry Name | PSB5_HUMAN |
| Gene Symbol | PSMB5 |
| GeneID | 5693 |
| NCBI Accession | NP_002788.1 |
| KEGG | hsa:5693 |
| String | 9606.ENSP00000355325 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 22/28 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |