Proteasome Subunit Beta Type 8 (PSMB8) Antibody

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Catalogue No: abx011689
Price: US$449.50
(Size: 100 µl)
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Western blot analysis using PSMB8 antibody against human PSMB8 (AA: 1-272) recombinant protein. (Expected MW is 55.2 kDa).
Proteasome Subunit Beta Type 8 (PSMB8) Antibody Proteasome Subunit Beta Type 8 (PSMB8) Antibody Proteasome Subunit Beta Type 8 (PSMB8) Antibody Proteasome Subunit Beta Type 8 (PSMB8) Antibody Proteasome Subunit Beta Type 8 (PSMB8) Antibody Proteasome Subunit Beta Type 8 (PSMB8) Antibody

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Datasheet SDS
Proteasome Subunit Beta Type 8 (PSMB8) Antibody is a Mouse Monoclonal against Proteasome Subunit Beta Type 8 (PSMB8) Antibody. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.

Target Proteasome Subunit Beta Type 8 (PSMB8)
Clonality Monoclonal
Reactivity Human, Rat
Tested Applications ELISA, WB, IHC, IF/ICC
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human PSMB8 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P28062 (UniProt, ExPASy)
UniProt Secondary AC B0UZC0, Q29824, Q5JNW6, Q5QNR8, Q96J48
UniProt Entry Name PSB8_HUMAN
Gene Symbol PSMB8
GeneID 5696
OMIM 177046
NCBI Accession NP_004150.1 NM_004159.4 NP_683720.2 NM_148919.3
KEGG hsa:5696
String 9606.ENSP00000364016
Molecular Weight 30 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Proteasome Subunit Beta Type 8 (PSMB8)
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