26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody

REQUEST MORE INFO
Catalogue No: abx037813
Price: US$391.50
(Size: 100 µg)

Click on the image to see the image legend

Available Options

* Size:

Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
Rabbit Polyclonal against the 26S Proteasome Regulatory Subunit 6A (PSMC3) protein. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Target 26S Proteasome Regulatory Subunit 6A (PSMC3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A peptide corresponding to middle region of human PSMC3 protein.
Isotype IgG
Form Lyophilized
Purification Purified by antigen affinity column chromatography.
Reconstitution Reconstitute in 100 µl of sterile distilled H2O with 50% glycerol.
Storage Store at -20 °C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17980 (UniProt, ExPASy)
UniProt Secondary AC B2R8V1, Q3B757, Q3B865, Q53HU5, Q6GPG8, Q6IBS1, Q96HD3
UniProt Entry Name PRS6A_HUMAN
Gene Symbol PSMC3
GeneID 5702
OMIM 186852
NCBI Accession NM_002804
HGNC 9549
KEGG hsa:5702
Ensembl ENSG00000165916
String 9606.ENSP00000481029
Molecular Weight Observed MW: 49 kDa
Buffer Prior to lyophilization: 1% BSA and 0.02% NaN3.
Concentration Lyophilized form: Not applicable.
After reconstitution: 1 mg/ml.
Availability Shipped within 7-15 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Regulatory Subunit 6A (PSMC3)


Write a review

Tags:
(Click to show)